Male Infertility Tests

The male infertility evaluation semen analysis is one of the most important tests conducted in the workup of the infertile couple. Studies show that approximately 47% of couples with infertility have a male factor component.

Given the importance of the semen analyses, it is best to have the test performed by a reproductive medicine laboratory. There are many quantitative and qualitative sperm characteristics that must be evaluated and these laboratories have the most experienced personnel. This test must be interpreted properly.

In addition to the standard semen analysis, other tests of sperm function might include tests for antisperm antibodies, cultures to detect microorganisms, and others. In addition to the semen analyses, a male hormonal evaluation is sometimes performed.

Sometimes more than one semen analyses is necessary as sperm quality and quantity can vary for numerous reasons. The sample is produced by masturbation at the reproductive medicine laboratory.

Reproductive labs use the "Kruger strict criteria" which assesses the following factors:

  • Volume (amount of fluid which makes up the semen, usually expressed in milliliters).
  • Sperm count (number of sperm in a standard given volume).
  • Motility (percent of sperm that are moving when the semen is examined under the microscope).
  • Progression (forward movement of sperm cells).
  • Viability (percent of sperm that are shown to be alive by use of a special staining technique).
  • Sperm morphology (shape) and additional semen contents, such as white blood cells (which can indicate the presence of infection).

Other conditions, such as a varicocele, can obstruct the flow of semen and the physician will screen for multiple factors.

Intracytoplasmic sperm injection (ICSI) is the treatment of choice for moderate to severe male factor infertility and gives hope to couples who previously had no chance of creating a genetically related child. A single sperm can usually be withdrawn from the male reproductive tract even if it is absent in the ejaculate. Please review our specialists articles for more information.

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